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Background
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Aim
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- Examine mortality (or prognostic implications)
in relation to coronary artery disease (CAD)
- Examine mortality (or prognostic implications)
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Method
- Published in 2011
- Multicenter CTA of the coronary arteries
- consecutive cohort of 23,854
- without known CAD
- who presented with.
- chest pain
- atypical or
- typical
- chest pain
- Time to mortality was estimated using multivariable Cox proportional hazards models.
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Result
- Identified and classified CAD
- none (0% stenosis),
- mild (1% to 49% stenosis),
- moderate (50% to 69% stenosis), or
- severe (>70% stenosis).
- 3 year survival without known CAD
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Data from PROMISE Study PROMISE Study
Survival related to number of vessels involvedSurvival Related to Number of Vessels Involved
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Calcified and Non-Calcified Plaque
Reconstruction of the coronary arteries shows predominantly non calcified plaque resulting in an elongated stenosis of the proximal LAD (maroon arrows) and short segment stenoses of the proximal RCA (red arrow) circumflex (blue arrow) and diagonal (white arrow) Scattered calcifications are lees prominent in the RCA and circumflex lesions
Ashley Davidoff thecommonvein.net
44047b
- Identified and classified CAD
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Conclusion
- Among individuals without known CAD, nonobstructive and obstructive CAD by CCTA are associated with higher
rates of mortality, with risk profiles differing for age and sex. - Importantly, absence of CAD is associated with a
very favorable prognosis.
- Among individuals without known CAD, nonobstructive and obstructive CAD by CCTA are associated with higher
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Relevance
- When we identify CAD on any patient who is having a CT scan it is important to make note of
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Links and References