Coronary CTA PROMISE Study

  • Background

    • 2015
    • How to deal with new onset stable chest pain
    • There was no no consensus
      • re  most appropriate diagnostic test to evaluate patients
  • Most patients received stress tests
    • stress – echo/SPECT/EKG
      • with limited accuracy
    • Hypothesis
      • initial anatomic testing  would result in superior long-term health outcome
        as compared to an initial functional testing strategy

  • Aim

    • Anatomical (CTA )vs Functional testing (Stress)
    • for
      • new-onset chest pain in patients
      • without known CAD

  • Method

    • 10,003 patients

  • Result

  • PROMISE Trial
    No difference in major outcomes MACE
    CTA vs Stress test

  • Conclusion

  • Relevance

 

Links and References

PROMISE Trial NEJM

The PROMISE Trial Noninvasive testing strategies in symptomatic, intermediaterisk CAD patients: a perspective on the “PROMISE” trial and its potential implementation in clinical practice

OberweissB S and Taylor A. J The PROMISE Trial The CTA Perspective ACC  July 28th 2015

PROMISE Study JAMA follow up for Plaque Characterization 2018