LV Mass and LV Mass Index

Left ventricular mass and left ventricular mass indexed to body surface area estimated by LV cavity dimension and wall thickness at end-diastole.

In a Nutshell

Mass: Normal  90 -100  gm/m2

Method

• Evaluation on short axis parallel to the true LV short axis
• LV mass is measured at a single time point within the cardiac cycle (the standard is end-diastole)
• single breath-hold removes respiratory artifact.
• About 10 slices will cover the ventricle,
• Simpson’s method (“stack of disks”)
• calculated from the
  • product of the myocardial volume
    • difference between the epicardial and endocardial LV volumes by a semi-three dimensional data set
  • specific gravity of heart muscle (1.05 g/ml).

BSA Calculator 

Normal Values have such a wide range depending on sex age and race – Echo and MR measurement are fairly consistent

Females about 60 g/m²
Males about 70 g/m²

LV mass was significantly higher in males compared to females (mean ± SD of 53 ± 9 g/m² vs 42 ± 7 g/m²). Petersen et al JCMR

Normal values of LV mass indexed to body surface area were found to be 70  (+/- 6-9 g/m² in men and 61 (+/- 6 -8 g/m² in women. Mizukoshi, showed echo and MR good correlation

Normal values of LV mass indexed to body surface area were found to be 60  (+/- 9 g/m² in men and 49  (+/- 7 g/m² in women). Fuchs EHJ CV Imaging

Reference Ranges & Partition Values for LV Mass Indexed To BSA (g/m²)

	Female	Male
Reference Range	43-95	49-115
Mildly Abnormal	96-108	116-131
Moderately Abnormal	109-121	132-148
Severely Abnormal	≥122	≥149

 

Mizukoshi, Left ventricular mass quantitation using single-phase cardiac magnetic resonance imaging. Am J Cardiol. 1992 Jul 15;70(2):259-62.

Mizukoshi, MD,  et al CLINICAL INVESTIGATIONS
LEFT VENTRICULAR MASS AND FUNCTION
Normal Values of Left Ventricular Mass Index Assessed
by Transthoracic Three-Dimensional
Echocardiography

 

See Map of  Left Ventricle